ACSL5 and systemic lupus erythematosus: As shown in Figure 1A, comparing with healthy subjects, freshly collected PBMCs from SLE patients had higher expression levels of mRNA for ACSL5 than controls [median (range); CTL = 16.5 (12.3–18) vs. SLE = 26.5 (17.8–41.7), P = 3.9×10−5].