STAT6 and asthma: It is also well established that STAT6 is important for the development of asthma [34], [35], [36] and a study on US population by Fessler, et al in 2009 has shown that serum total cholesterol and non-HDL-cholesterol are inversely related to asthma [37], thereby further pointing towards the inverse relation between STAT6 and cholesterol.