Images of the region of the 2-DE showing spot 02 (Mn-SOD, up-regulated 3.1-fold), spot 03 (ERp29, up-regulated 4.7-fold) and spot 08 (HSP27, up-regulated 3.9-fold) in the RR NPC tissues compare to the RS NPC tissues are shown in Fig. 1B. The gene discussed is SOD2; the disease is nasopharyngeal carcinoma.