Several proteins, Epstein-Barr virus gene BHRF1 (5), antioxidant enzyme manganese superoxide dismutase (MnSOD2) (6), 14-3-3σ (7), and raf kinase inhibitory protein (RKIP) (8) have been proved to be associated with radioresistance in NPC. The gene discussed is SOD2; the disease is nasopharyngeal carcinoma.