As shown in Fig. 1B, correlation appears to be negative between the expression of Mirk protein and the total level of FoxO (FoxO1+FoxO3A) in ovarian cancer cells (R2=0.946 and P<0.001), suggesting FoxO1 and/or FoxO3A may be associated with Mirk function or kinase activity. This evidence concerns the gene FOXO3 and ovarian cancer.