EGFR and glioblastoma: In glioblastomas (data not shown), PFS was significantly better for patients with no EGFR amplification (5.4 vs. 8.4 months, p=0.01), no expression of EGFRvIII mutant mRNA (3.7 vs. 8.4 months, p=0.04), or weak EGFRv2 (3.3 vs. 5.6 months, p=0.04) or -v4 mRNA levels (8.4 vs. 4.7 months, p=0.05).