NFKB1 and Familial prostate cancer: Szlıszka et al. demonstrated that TRAIL (tumour necrosis factor-related apoptosis-inducing ligand)-resistant prostate cancer cells were sensitized by treatment of ethanolic extract of Brazilian green propolis (EEP) by enhancing the expression of TRAIL-R2 and the activity of NF-κB in LNCaP cells [20].