Carcinoembryonic Antigen (CEA) and Cytokeratin-19 fragment (Cyfra 21.1) with the optimum cutoff value 6 ng/ml and 3.3 ng/ml, respectively, are two best biomarkers for predicting NSCLC currently under investigation [12,26,27]. This evidence concerns the gene KRT19 and non-small cell lung carcinoma.