Upon wt TP53 expression, DanG-TREx-TP53 and the MiaPaCa-2-TREx-TP53 cells showed a distinct growth inhibition (Figure 1C), suggesting that exogenously induced wt TP53 was functionally intact in these pancreatic carcinoma cell lines. This evidence concerns the gene TP53 and exocrine pancreatic carcinoma.