IFNAR1 and infection: Similar to IFNAR-/- mice, all wild type mice treated with a single dose of MAR1-5A3 but not the isotype control GIR-208 MAb ranging from 0.3 to 2.5 mg succumbed to WNV-NY infection, although the mean time of death (MTD) was delayed (6.5 days versus 4 days, P<0.0001).