As shown in Figure 5, sequence analysis of the PKD1 gene in the ADPKD-iPS and WT-iPS cell clones confirmed the heterozygous W3842X mutation only in the ADPKD-iPS cell clone, demonstrating that cellular reprogramming did not affect the autosomal mutation in the PKD1 gene. Here, PKD1 is linked to autosomal dominant polycystic kidney disease.