SST and type 2 diabetes mellitus: Consistent with earlier reports, we observed a 56% decrease in β-cells mass (p = 0.03) and an ∼8% increase in α-cell mass that did not reach statistical significance (p = 0.41) while somatostatin cell mass was similar (p = 0.68) in pancreas sections from patients with T2DM compared to controls (Fig. 1a) [14], [15], [16].