More interestingly, increasing levels of KIR3DS1 RNA transcripts were strongly associated with the level of HIV-1 inhibition in all KIR3DS1-carrying individuals expressing the putative ligand (r2 = 0.81, p<0.001, Figure 5B), whereas the relative expression of KIR3DL1 was not associated with NK-cell-mediated inhibition of HIV infection (Figure 5C). Here, KIR3DL1 is linked to HIV infectious disease.