PPARG and systemic sclerosis: In contrast, α-SMA, CTGF, and NF-κB were reduced by rosiglitazone treatment to a similar extent in SSc-ILD fibroblasts derived from either black or white subjects, suggesting that the PPARγ agonist reduces α-SMA, CTGF, and NF-κB by a mechanism(s) independent of HGF.