In addition, as shown in Fig. 5E, DiOC6 fluorescence of AML (M1) ALDHhi/CD34+ cells was not reduced 3 days after transfection with IER5 cDNA or TMPP treatment, and DiOC6 fluorescence of IER5 cDNA-transfected or TMPP treated cells compared to control cells was observed in the almost same levels. The gene discussed is CD34; the disease is acute myeloid leukemia.