Furthermore, we recently demonstrated that animal models of PD prepared by administration of neurotoxins such as 6-hydroxydopamine (6-OHDA) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) involved the oxidative modification of DJ-1 in the brain and erythrocytes [17]. The gene discussed is PARK7; the disease is Parkinson disease.