For instance, high levels of the kallikrein-kinin components, namely des-Arg9-bradykinin (DABK), bradykinin, kallikrein-1 and kallikrein-6, as well as low-molecular-weight kininogens (KNGL), have been found in the CNS tissue and cerebrospinal fluid from both animals with EAE and MS patients [16], [17]. This evidence concerns the gene KNG1 and myeloid sarcoma.