Our bioinformatic analysis revealed several GR-responsive and related elements (GREs) in the promoter regions of SLIT2, SLIT3, ROBO1, ROBO2 and ROBO4. Intriguingly, in neuroblastoma cells, the activated GR directly interacts with p53 and inhibits p53 dependent cell cycle arrest and apoptosis [45]. The gene discussed is ROBO1; the disease is neuroblastoma.