Finally, the abundance of leukemia initiating cells, which are present in the haematopoietic stem cell compartment (Lin- Sca-1+ c-kit+) (LSK) expressing BCR-ABL1 [40], was significantly reduced based on a partial MHC-I deficiency of the graft relative to the host (Fig. 6A, C). This evidence concerns the gene KIT and leukemia.