In the PBMCs of patients with congenital cataracts, the expression of TGFβ3 (Me=9395) was the highest and significantly greater than those of TGFβ1 (Me=4475, p=0.015, post hoc test) and TGFβ2 (Me=343, p<0.001). The gene discussed is TGFB3; the disease is early-onset non-syndromic cataract.