Interestingly, the subjects with congenital cataracts showed a significant elevation of TGFβ1 and TGFβ2 expression in PBMCs when compared to those with traumatic cataracts, which suggests that traumatic cataractogenesis is mediated differently from congenital cataractogenesis. Here, TGFB1 is linked to early-onset non-syndromic cataract.