Analysis revealed the most significant pathways included allograft rejection, antigen processing and presentation, cell adhesion molecules, complement and coagulation cascades, graft-versus-host disease, Type I diabetes mellitus, autoimmune thyroid disease, cytokine-cytokine receptor interaction, natural killer cell mediated cytotoxicity, RIG-I-like receptor signaling pathway, and the p53 signaling pathway. The gene discussed is TP53; the disease is graft versus host disease.