Monocyte derived DCs obtained from 6 healthy donors were treated with 1 in 2 TCM of 21 colorectal patients for 4 hours before treatment with LPS for a further 18 hours, and interestingly, TCM treated DCs secreted significantly higher levels of IL-10 in response to LPS (p<0.0001), but significantly lower levels of IL-12p70 (p<0.0001) (Figure 2A). The gene discussed is IL10; the disease is medical procedure.