SNP rs1265181 in HCG27 is the top association signals in a GWAS of psoriasis in Han Chinese population [11], while rs130065 in CCHCR1 has been consistently associated with psoriasis in multiple populations [25], [26], [27], and HCR1 protein expressed differently between lesional skin and normal skin [26]. The gene discussed is CCHCR1; the disease is psoriasis.