To determine if the corticosteroids dexamethasone and fluticasone and the β2 agonist salmeterol could inhibit RV-induced IL-6 and IL-8 and RV replication, tissue culture medium from fibroblasts pretreated with drug for 1 hour and then infected with RV was analysed by ELISA after 48 hours and RV titration 24 hours post infection. The gene discussed is CXCL8; the disease is infection.