There were 10 patients with normal ALT and moderate/severe fibrosis on liver biopsy; 4 of these patients had >3 log copies/mL HBV DNA levels and 6 patients were misclassified as “inactive carriers” with negative HBV DNA levels and normal ALT (6/84−7% of total HBeAg− group) (Table 3). The gene discussed is GPT; the disease is fibrosis.