A range of clinical multimodal studies have been conducted examining the combined effects of Ibuprofen and megestrol acetate [14], COX-2 (celecoxib), Medroxyprogesterone acetate and oral food supplements [28], and home total parenteral nutrition, anti-inflammatory (indomethacin) and erythropoietin therapy on cachexia [29]. This evidence concerns the gene PTGS2 and Cachexia.