In addition to its antioxidant properties, it has been shown to possess antifibrotic, anticancer, and anti-inflammatory activities regulating both TGF-β and PDGF-induced α1(I) collagen, fibronectin, α-smooth muscle actin (α-SMA), and proliferation in activated human and rat hepatic stellate cells [108–110], rat pancreatic cells [111, 112], human keloid fibroblasts [113], and SSc dermal fibroblasts [114]. This evidence concerns the gene TGFB1 and systemic sclerosis.