AIDS presenters featured lower CD127+CD4+% (median CD127+CD4+%: AIDS presenters 6, IQR 4–11—N-AIDS presenters 14, IQR 8–21; P = 0.0001), higher CD95+CD8+% (median CD95+CD8+%: AIDS presenters 3, IQR 2–6—N-AIDS presenters 1, IQR 2–4; P = 0.003), CD38+CD8+% (median CD38+CD8+%: AIDS presenters 12, IQR 5–23—N-AIDS presenters 6, IQR 2–11; P = 0.0001), and CD45R0+CD38+CD8+% (median CD45R0+CD38+CD8+%: AIDS presenters 16, IQR 10–25—N-AIDS presenters 11, IQR 7–19; P = 0.02). This evidence concerns the gene CD4 and AIDS.