CD8A and mitochondrial DNA depletion syndrome 4a: Interestingly, CD8+% (AOR 1.061 for each unit more, 95%CI 1.031–1.093, P = 0.0001), CD8+CD38+% (AOR 1.066 for each unit more, 95%CI 1.009–1.126, P = 0.022), CD8+CD38+CD45R0+% (AOR 0.955 for each unit more, 95%CI 0.993–0.997, P = 0.0001), and CD4+CD127+% (AOR 0.837 for each unit more, 95%CI 0.792–0.884, P = 0.0001) were significantly associated with AHD, also after controlling for age and risk groups for HIV infection (Supplementary Table 2).