HIF1A and transient ischemic attack: In the present study, we determined the effects of inhibiting HIF-1 by YC-1 (3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole, Fig. 1), an established HIF-1 inhibitor, on ischemic outcomes in a rat model of transient cerebral ischemia with the following parameters: infarct volumes and BBB permeability.