We are aware of only two previous studies relating IFIH1 variants to enterovirus RNA in humans, one that investigated the common rs1990760 but which was severely underpowered for genetic association analysis [25] and one relatively large study of young adult patients with established type 1 diabetes (and non-diabetic controls) that investigated two rare type 1 diabetes IFIH1 variants (rs35744605 and rs35667974) [26]. Here, IFIH1 is linked to type 1 diabetes mellitus.