In contrast, Wsh+WT+IL-4 mice recruited significantly more neutrophils than Wsh+WT controls 4 h after Klebsiella infection, as also observed in wild type Nippo mice (Fig. 3), suggesting that IL-4 conditioning of mast cells in vivo contributes to the survival advantage in Nippo mice. The gene discussed is IL4; the disease is Klebsiella Infections.