In SjS, the newly reported candidate genes and risk loci include early B-cell factor 1 (EBF1) gene, family with sequence similarity 167 member A (FAM167A)-BLK locus, TNF superfamily4 gene, HLA-DRB1∗0301, -DQA1∗0501, and -DQB1∗0201, with SNPs in IL-10 promoter, Fas/FasL, TGF-β1, and TNFα genes, IRF5 and STAT4 [44]. Here, TNF is linked to Schwartz-Jampel syndrome.