Similarly, Nrp1 (Supporting Information Table S9), which shows a similar expression pattern to Nelf within gonadotropin-releasing hormone neurons, but is also expressed by cortical interneurons (Marín et al., 2001), has been suggested to play a role in the aetiology of hypogonadotropic hypogonadism (Cariboni et al., 2011). This evidence concerns the gene NRP1 and hypogonadotropic hypogonadism.