qilinhi3595A heterozygote in-crosses injected with ΔCC mRNA developed curvature and kidney cysts at an average of 18.9% from three experiments, not significantly different from uninjected embryos where an average of 24.7% of the embryos developed curvature and kidney cysts (Fig. 8B), suggesting that the coiled-coil domain is necessary for Qilin's functions. The gene discussed is IFT38; the disease is Kidney Cyst.