KLK5, 6 and 10 are detectable in the ascites of ovarian cancer patients at the relatively high average concentrations of 62.2 ng/ml, 144 ng/mL, and 57 ng/ml respectively [16], however few studies have addressed the differences in ascites and serum concentrations of kallikreins on the basis of histological subtypes in a large cohort of ovarian cancer patients. This evidence concerns the gene KLK4 and ovarian cancer.