MAP1LC3A and mucopolysaccharidosis type 3B: These include proteins involved in autophagy: LC3, P62, and polyubiquitinated protein(s) [29]; nitrotyrosine-modified protein(s), a marker for oxidative stress, which has been reported in MPS IIIB brain [5]; and O-GlcNAc-modified protein(s), a marker for metabolic stress [30].