Expression of PHF3 and PTP4A1 transcripts was significantly correlated with expression of many alcoholism-related genes in brain, including those in the dopaminergic, serotoninergic, GABAergic, glutamatergic, histaminergic and endocannabinoid systems [6], [17], [18], [19], [20], [21]. This evidence concerns the gene PTP4A1 and alcohol dependence.