With the insertion of K1L and C7L, this response was tempered; infection with NYVAC-C-KC-ΔB8RΔB19R induced increased transcriptional levels of seven of the genes shown, relative to NYVAC-C-KC (IFI35, IFI44, IFI44L, IFIT1, IFIT3, IFITM1, and IFITM2). Here, IFIT1 is linked to infection.