These observations are in agreement with the findings of Kim et al (2009) of a redistribution of the eEF1A proteins: tumour cells promote cell growth and invasion by activating and maintaining membrane-based ion exchangers reversing the pH gradient across cell membrane (intracellular alkalinisation), thus causing the release of eEF1A proteins from actin filaments and their migration in different cellular compartments. This evidence concerns the gene EEF1A1 and neoplasm.