The following mutations in cervical cancer samples have been registered in the Sanger database by order of frequency: STK11 (serine threonine kinase) (29/201: 14%), Hras (23/263: 9%), Kras (46/636: 7%), PIK3CA (25/255: 10%), CDKN2A (23/267: 9%); in addition loss of PTEN has been documented in 16 cases. The gene discussed is STK11; the disease is cervical carcinoma.