Unique proteins to the CKD group were Antithrombin-III (SERPINC1), Complement factor H-related 1 (CFHR1), Desmoglein-2 (DSG2), Lumican (LUM), Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE1), Pigment epithelium-derived factor (SERPINF1), Thyroxine-binding globulin (SERPINA7), and Zinc-alpha-2-glycoprotein (AZP1). The gene discussed is SERPINC1; the disease is chronic kidney disease.