In non-ACoTS patients, SBE correlated negatively with Annexin V (P = 0.003), syndecan-1 (P = 0.004), D-dimer (P = 0.018) and IL-6 (P = 0.038) and positively with sEPCR (P = 0.029) (the latter also observed in ACoTS patients, P = 0.039). Here, IL6 is linked to subacute bacterial endocarditis.