It is noteworthy that SNPs rs610604 (in TNFAIP3), rs187084, rs352140 and rs352162 (in TLR9) showed a rather low effect size (odds ratio (OR) = 1.00 to 1.04), implying that they have almost no or a rather weak contribution to SLE pathogenesis in the Chinese population. This evidence concerns the gene TNFAIP3 and systemic lupus erythematosus.