A total of six SNPs were found to be significantly related to SLE (P < 0.05, Table 1), and five of them remained significant after Bonferroni correction, including three SNPs in TNFAIP3 (rs5029924, rs5029937 and rs2230926) and two SNPs in ETS1 (rs6590330 and rs4937333). The gene discussed is TNFAIP3; the disease is systemic lupus erythematosus.