PNPLA3 and liver cancer: The frequency of the PNPLA3 148M allele was increased both in alcohol-induced cirrhosis (OR = 1.92; 95%-CI: 1.28–2.86; p<0.002) and alcohol-associated liver cancer (OR = 4.37; 95%-CI: 2.97–6.43; p<0.001) as compared to healthy controls.