FOS and infection: The data demonstrate that vaginal ECs direct a specific and organized response to C. albicans, whereby changes in transcription factor binding activity occurred at 3 h post-infection, with distinct profiles of activity that either mirror (c-Fos increased and MEF2 decreased) or differ (c-Jun increased at 3 h, Elk-1 increased at 3 h, not decreased at 2 h) from those seen in oral ECs.