In a series of experiments comparing the expression of CYP24A1 in response to 1α,25(OH)2D3 and MART-10 treatment in LNCaP and PC-3 prostate cancer cells, we observed that MART-10 was capable of inducing CYP24A1 expression at a lower concentration and to a greater extent [54] and with a longer duration than 1α,25(OH)2D3 (D. Iglesias-Gato et al., unpublished observation). Here, CYP24A1 is linked to Familial prostate cancer.