S100A8 and gastric adenocarcinoma: As shown in Figure 3(b), neither cagA nor vacA genotype was not correlated with clinical disease in spite of critical pathogenic contribution in our documentation in spite that the presence of cagA is associated with increased risk of gastric adenocarcinoma [25] and that statistical significance exists between bacterial genotype of CagA allele, VacA allele, and host disease status [26].