CD8A and ovarian neoplasm: Importantly, DCs loaded with HOCl-oxidized SKOV3 ovarian tumor lysate but not pulsed with peptides efficiently presented endogenous HER-2/neu antigen to HER-2/neu specific CD8+ T cells (but not to MART-1 specific CD8+ T cells) [Figure 3B, left and right bottom panels], consistent with expression of HER-2/neu by SKOV3 cells.