ERBB2 and carcinoma: The pCR rates in HER2-positive carcinomas (28% without and 52% with neoadjuvant trastuzumab treatment) were higher than in the NOAH study (19% and 38%) [20], GeparQuattro study (31.7% for patients treated with trastuzumab) [21], and TECHNO study (42% for patients treated with trastuzumab) [22], but the sample sizes in the present study were much smaller.