Consistent with CIP2A mRNA expression profile, the presence of the CIP2A protein was found in 75 of 107 (70%) of cancer samples, whereas only 6 of 19 (32%) tumour adjacent tissues and 1 of 6 (17%) normal renal tissues exhibited weak or diffuse CIP2A expression (P<0.0001). This evidence concerns the gene CIP2A and cancer.