Additional studies with the human colon cancer cells SW620, and the derived from them SW620R cells, that grow at 3 mM butyrate, indicated that these cells do not express detectable levels of ROR2 (data not shown); however, they express WNT5A, and exposure to butyrate increases pAKT levels (Fig. 2E). The gene discussed is ROR2; the disease is malignant colon neoplasm.