Analyses of additional pair of colon cancer cells lines, SW620 cells and the derived from them SW620R cells, that grow at 3 mM butyrate, revealed that both cell lines do not express detectable levels of ROR2 (data not shown); however, they express WNT5A, and increase the levels of pAKT in the presence of butyrate (Fig. 2E). Here, ROR2 is linked to colonic neoplasm.